Also subjektive Meinungen von ein paar Anwendern sind denkbar schlecht, um sich ein gutes Bild über irgendeinen Zusammenhang zu machen. Da helfen eher wissenschaftlich einwandfreie Studien.
D.h. am besten suchst du nach solchen Studien.
Der Artikel auf Wikip. stützt ja die Aussagen auf ebensolche Studien.
Auf Pubmed gibt es paar Artikel, jedoch sind die meisten mit Versuchstieren gemacht; solche Ergebnisse kann man nicht 1:1 auf Menschen übertragen.
Eine Sache die man findet ist z.B:
Zitat:
First long-term CLA study shows body fat reduction
Jean-Michel Gaulliers "Efficacy and Safety of One-year Supplementation with Conjugated Linoleic Acid in Moderate Overweight," presented at the 2003 American Oil and Chemist Society's Meeting, showed that CLA (conjugated linoleic acid) reduced body fat by 9% and increased lean muscle by 2%. The effects on body composition were produced by trials performed with a mix-hire of the bioactive isomers (cis-9, trans-11 and trans-10, cis-12).
Overweight subjects were randomized in three groups, and supplemented for one year either with CLA given as free fatty acid, or as triglycerides, and compared with a placebo (olive oil). Measurements performed with dual-energy X-ray absorptiometry show significant changes over time. Cognis Nutrition and Health, Duane Fimreite, 708-579-6215
Oder eine Meta-Analyse:
Zitat:
Appl Physiol Nutr Metab. 2009 Oct;34(5):975-8.
A meta-analysis of the effects of conjugated linoleic acid on fat-free mass in humans.
Schoeller DA, Watras AC, Whigham LD.
Department of Nutritional Sciences and Obstetrics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Treatment of laboratory animals with a 50:50 mixture of c9,t11 and t10,c12 conjugated linoleic acid (CLA) results in fat loss and, to a smaller degree, fat-free mass (FFM) gain. In a previous meta-analysis, we found that CLA produced a fat loss, but that humans were not as responsive as mice. We performed a similar meta-analysis in the same 18 studies to test whether CLA increased FFM. Only placebo-controlled trials that measured body composition were included. We found that FFM increased during CLA treatment (0.3 +/- 0.7 kg; p = 0.05), but that the change did not display an effect of length of treatment (0.001 +/- 0.005 kg.week(-1); p = 0.8), or an effect of dosage (0.1 +/- 0.1 kg.g CLA(-1).day(-1); p = 0.3). We conclude that FFM does increase in humans during CLA treatment, but the onset of the increase is rapid and the total increase is small (<1%).
PMID: 19935864
Noch eine:
Zitat:
Arch Latinoam Nutr. 2009 Sep;59(3):245-52.
Effect of conjugated linoleic acid (CLA) on human lipid profile
Agueda M, Zulet MA, Martínez JA.
Departamento de Ciencias de la Alimentación, Fisiología y Toxicología, Universidad de Navarra, Pamplona, España.
The term conjugated linoleic acid (CLA) concerns a group of isomers of linoleic acid, which are characterized by having conjugated double bonds in several positions and conformations. CLA is found naturally in some foods, but since CLA was first held to cause beneficial effects on various health-related issues, many investigations have been conducted to elucidate the effects of dietary supplementation with CLA. The effects of CLA on lipid profiles on animals have been extensively studied, and there is sound evidence of its benefits in blood metabolic markers. However, clinical trials in humans have provided ambiguous results. The aim of this review was to gather up-to-date available data about the effects of CLA on human lipid profile. Although most studies did not show any significant effect in none of the studied variables, some trials reported both beneficial and detrimental effects on total cholesterol, LDL-c, HDL-c, atherogenic index, triglycerides and lipoprotein(a). This discrepancy could be due to differences in dosage, isomer composition, duration of the study, placebo and participating subjects, among others. However, studies with a duration of two weeks, carried out using a mix of equal amounts of the two main CLA isomers (9-cis, 11-trans and 10-trans, 12-cis) and with doses of 3 to 4 grams per day, seem to offer the most beneficial results.
PMID: 19886508
Die kommerziell angebotenen CLA-Produkte werden idR alle dasselbe enthalten, also wichtig ist, dass die (idR zwei) aktiven Isomere (9-cis, 11-trans and 10-trans, 12-cis) drin sind.
