Mike says that our muscles are 70% water, 22% Protein, 6% fat, and another 2% "Inorganic Material", fair enough. He also says that 1 pound of muscle contains 600 calories. So by Mikes reasoning in order to gain 10lbs of lean muscle a year one would need to take in 6000 calories above maintenance per year (600 calories per pound X 10lbs desired muscle gain). By continuing to divide that 6000 calories over the course of 365 days (number of days in a year), Mike says that we
only need 16 extra calories above maintenance per day to gain 10lbs of muscle in a year. Furthermore, Mike states that since our muscles are only about 25% protein, then we only need 4 calories of that extra 16 to come from protein because 25% of 16 is 4 and 1 gram of protein equals 4 calories.
So according to Mike Mentzer, increasing your daily caloric needs by 16, with
4 of those calories coming from 1 gram of protein, results in 10lbs of muscle in one year. Or saying it another way;
Increasing your protein intake by 1 gram above maintenance per day would result in 10lbs of muscle in one year.
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